Hemoglobin & Myoglobin: 4. Dissociation Curves - Biochemistry Flashcards
4.5 (202) In stock
Dissociation Curves We can compare compare the binding properties of both myoglobin and hemoglobin by drawing their dissociation curves. These curves measure their relative affinities for oxygen. • We draw a graph and label the x-axis oxygen partia
Dissociation Curves We can compare compare the binding properties of both myoglobin and hemoglobin by drawing their dissociation curves. These curves measure their relative affinities for oxygen. • We draw a graph and label the x-axis oxygen partial pressure (torr). Number it 0 to 120. – 30 torr is ~ the partial pressure of oxygen in the body's tissues. – 100 torr is ~ the partial pressure in the lungs. • The y-axis % oxygen saturation: it's numbered 0 to 100. We will use it to compare the oxygen binding patterns of both hemoglobin and myoglobin. oxygen binding curve for hemoglobin and myoglobin Hemoglobin • We draw a sigmoidal curve that plateaus just below 100% saturation. • Cooperative binding produces this sigmoidal shape. – As one oxygen molecule binds, hemoglobin's affinity for additional oxygen increases, and its percent saturation rapidly increases. • We show that hemoglobin reaches half saturation in the peripheral tissues – it responds to oxygen availability and releases it when partial pressure is low. Myoglobin • We draw a hyperbolic curve to the left of the hemoglobin curve, a much simpler binding pattern that corresponds to myoglobin's single heme group. – Myoglobin has a high affinity for oxygen, and does not release it until the partial pressure is very low. – These binding properties correspond to myoglobin's role in oxygen storage. – We label the early portion of the curve "Exercising muscle" and the plateau "Muscle at rest." Myoglobin vs. Hemoglobin • Myoglobin releases oxygen in response to the muscle's immediate needs. • Hemoglobin's cooperative binding allows it to respond to changes in oxygen availability. Fetal hemoglobin dissociation curve • As a clinical correlation, we show that the fetal hemoglobin dissociation curve is to the left of the adult hemoglobin curve. • This is because it has a greater affinity for oxygen to facilitate oxygen transfer from the maternal hemoglobin to the fetus; fetal oxygen supplies come from the mother.
Evolution of Myoglobin and Hemoglobin Leaders in Pharmaceutical Business Intelligence (LPBI) Group
Oxygen dissociation curve for a mouse.
Biochemistry I Chapter 7 Problems Flashcards
physiology - Cooperativity of haemoglobin and oxygen dissociation curve of haemoglobin - Biology Stack Exchange
Biochemistry Hb Flashcards
Biochemistry Chapter 7 Flashcards
What is the O2-Hemoglobin dissociation curve, and what factors and how can affect it? - Quora
Oxygen Myoglobin Dissociation Curve
D.6 Gas Transport
Biochemistry Exam 2 Flashcards
1st Unit / Ch 3 Globular Proteins Flashcards by ROSCIAE SAVIOR
Oxygen-hemoglobin dissociation curve: Video & Anatomy
Ditki, Medical & Biological Sciences - Answers: hemoglobin-myoglobin-4-dissociation-curves #ditki #physiology #usmle #usmlestep1 #meded #medicalschool #medicalstudent
Oxygen Transport - an overview
Exploring the Structure and Function of Myoglobin and Hemoglobin Through Animations, Illustrations, and Lectures, PDF, Hemoglobin
HEMO Body Saper Bodysuit Shapewear For Women Tummy Control Body
HEMO Body Saper Bodysuit Shapewear Waist Trainer Butt Lifter Sexy
Creating a visualization system for changes in facial shape and
- Laney Triangle Bralette – Nette Rose
- Uniqlo U + Ultra Light Down Jacket
- OTTER-Messer Large Pocket Knife Lockback Brown Buckhorn Stainless Blad – Atlantic Knife Company
- Hot Pink Elastic Waist Wide Leg Pants
- Special Design Panties With Pocket For Tummy Warm Women at Best
- Victoria's Secret on X: The new T-Shirt Bra will make anyone a morning person. #wearitdaily #XOVictoria / X