A schematic model of Lewy body formation
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![](https://www.researchgate.net/publication/331752623/figure/fig1/AS:736526124191744@1552612920015/A-schematic-model-of-Lewy-body-formation.png)
![](https://www.researchgate.net/profile/Xinhe-Wang-4/publication/256085992/figure/fig1/AS:297964791713793@1448051750437/De-novo-formation-of-rPrP-res-The-sPMCA-reaction-was-carried-out-with-a-substrate_Q320.jpg)
Xinhe WANG, Senior Research Scientist
![](https://www.biorxiv.org/content/biorxiv/early/2019/09/02/751891/F9.large.jpg)
The process of Lewy body formation, rather than simply alpha-synuclein fibrillization, is the major driver of neurodegeneration in synucleinopathies
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13578-021-00709-y/MediaObjects/13578_2021_709_Fig1_HTML.png)
α-Synuclein-mediated neurodegeneration in Dementia with Lewy bodies: the pathobiology of a paradox, Cell & Bioscience
![](https://media.springernature.com/m685/springer-static/image/art%3A10.1186%2Fs13024-019-0329-1/MediaObjects/13024_2019_329_Fig4_HTML.png)
Alpha-synuclein structure and Parkinson's disease – lessons and emerging principles, Molecular Neurodegeneration
![](https://pub.mdpi-res.com/diagnostics/diagnostics-11-02091/article_deploy/html/images/diagnostics-11-02091-g001.png?1636711462)
Diagnostics, Free Full-Text
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Andrew P Lieberman's research works
![](https://www.researchgate.net/publication/350814753/figure/fig1/AS:1018331909853185@1619800655438/Pathogenic-mechanisms-consistently-associated-with-Lewy-bodies-across-multiple.png)
Pathogenic mechanisms consistently associated with Lewy bodies across
![](https://www.researchgate.net/publication/366985016/figure/fig1/AS:11431281112110150@1673323299993/Evidence-of-subclinical-prion-infection-in-hamsters-inoculated-with-HSPWT-or-HSPDG54_Q320.jpg)
Jiyan MA, Doctor of Philosophy
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Nathan Levine's research works Van Andel Research Institute, Mi
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Animal models of Parkinson's disease: bridging the gap between disease hallmarks and research questions, Translational Neurodegeneration
![](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnrn.2017.75/MediaObjects/41583_2017_Article_BFnrn201775_Fig1_HTML.jpg)
Animal models of α-synucleinopathy for Parkinson disease drug development
![](https://c5.rgstatic.net/m/435982309481010/images/template/default/author/author_default_m.jpg)
PDF) Pathogenic alpha-synuclein aggregates preferentially bind to
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Life, Free Full-Text
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