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PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

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Incorporating Measures of Variability and Uncertainty into the

Prediction of hepatic clearance in human from in vitro data for

Mechanistic insights from comparing intrinsic clearance values

In Vitro-In Vivo Extrapolation and Scaling Factors for Clearance

PDF] NONLINEAR PHARMACOKINETICS OF PROPAFENONE IN RATS AND HUMANS

Precisely adjusting the hepatic clearance of highly extracted

Frontiers A Critical Perspective on 3D Liver Models for Drug

Exploring the Boundaries for In Vitro–In Vivo Extrapolation: Use

Use of Hepatocytes to Assess the Contribution of Hepatic Uptake to Clearance in Vivo

Incorporating Measures of Variability and Uncertainty into the Prediction of in Vivo Hepatic Clearance from in Vitro Data

Preclinical experimental models of drug metabolism and disposition

PDF) Clearance Prediction Methodology Needs Fundamental Improvement: Trends Common to Rat and Human Hepatocytes/Microsomes and Implications for Experimental Methodology

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