JCM, Free Full-Text
4.7 (639) In stock
We performed an animal study to identify the techniques associated with the best muscle healing outcomes in cleft lip/palate surgery. The right triceps of thirty adult male Sprague–Dawley rats were cut and repaired by three different suture techniques: simple (n = 10), overlapping (n = 10), and splitting sutures (n = 10). Muscle tissues were isolated from 5 rats per group 1 and 8 weeks postoperation. The inflammatory response and muscle fiber healing were evaluated by hematoxylin and eosin (H&E) staining, Western blotting, immunohistochemistry for TNF-α and IL-1β, and immunofluorescence for laminin and MyoD. Grip strength (N/100 g) and spatial gait symmetry were evaluated before surgery and 1, 2, 4 and 8 weeks postoperation. Eight weeks postoperation, grip force per weight was significantly higher in the simple suture (median, 3.49; IQR, 3.28–3.66) and overlapping groups (median, 3.3; IQR, 3.17–3.47) than the splitting group (median, 2.91; IQR, 2.76–3.05). There was no significant difference in range of motion between groups. The simple group exhibited significant remission of inflammation by H&E staining and lower expression of TNF-α and IL-1β than the other groups by Western blotting and immunohistochemistry. Immunofluorescence revealed stronger expression of MyoD and weaker expression of laminin in the splitting group than in the other groups at week 8, indicating prolonged inflammation and healing followed by poor muscle fiber remodeling. Simple and overlapping sutures demonstrated similar functional healing, although greater inflammation and failure to maintain a thicker muscle belly were observed in the overlapping suture group compared with the simple suture group. Therefore, reconstruction of the philtral column with overlapping sutures alone may result in limited long-term fullness, and additional procedures may be needed.
Marshall JCM 800 Combo Amp 1x12 4010
JCM, Free Full-Text, buona spray sol nasal
JCM, Free Full-Text, buona spray sol nasal
JCM, Free Full-Text, man blue skin
Trend frontier JCM, Free Full-Text, transcutaneous electrical
JCM, Free Full-Text
JCM, Free Full-Text
JCM Construction, LLC
Jcm Free Full Text Sex Differences Are Here To Stay Relevance To
JCM, Free Full-Text, halimeter
Post-Workout Muscle Recovery: How to Let Your Muscles Heal and Why
How Do Muscles Repair Themselves After Injury?
Muscle Transplant — Paralysis Center
Diastasis Recti Repair and Tummy Tuck Surgery - Miguel Delgado, MD
Is Muscle Repair with Tummy Tuck Always Necessary? - Power Plastic Surgery
- Make It Real Mini Juicy Couture Crystal Sunshine
- Christmas Tree Print Bikini Knickers, M&S Collection
- Sparkly Sequin Long Glitter Prom Tight Party Dress With Split
- Leggings Esportivas Plus Size Calças De Yoga De Academia Com
- Cacique, Intimates & Sleepwear
- Rite Aid files for bankruptcy, announces financial restructuring plans amid opioid complaints, lawsuits - ABC News