The role and therapeutic potential of stem cells in skeletal muscle in sarcopenia, Stem Cell Research & Therapy
4.9 (356) In stock
Sarcopenia is a common age-related skeletal muscle disorder featuring the loss of muscle mass and function. In regard to tissue repair in the human body, scientists always consider the use of stem cells. In skeletal muscle, satellite cells (SCs) are adult stem cells that maintain tissue homeostasis and repair damaged regions after injury to preserve skeletal muscle integrity. Muscle-derived stem cells (MDSCs) and SCs are the two most commonly studied stem cell populations from skeletal muscle. To date, considerable progress has been achieved in understanding the complex associations between stem cells in muscle and the occurrence and treatment of sarcopenia. In this review, we first give brief introductions to sarcopenia, SCs and MDSCs. Then, we attempt to untangle the differences and connections between these two types of stem cells and further elaborate on the interactions between sarcopenia and stem cells. Finally, our perspectives on the possible application of stem cells for the treatment of sarcopenia in future are presented. Several studies emerging in recent years have shown that changes in the number and function of stem cells can trigger sarcopenia, which in turn leads to adverse influences on stem cells because of the altered internal environment in muscle. A better understanding of the role of stem cells in muscle, especially SCs and MDSCs, in sarcopenia will facilitate the realization of novel therapy approaches based on stem cells to combat sarcopenia.
Regenerative decline of stem cells in sarcopenia.
Skeletal muscle - Wikipedia
Skeletal Muscle Metabolic Alternation Develops Sarcopenia
IJMS, Free Full-Text
Mitochondrial dynamics maintain muscle stem cell regenerative competence throughout adult life by regulating metabolism and mitophagy - ScienceDirect
Mitochondrial transplantation as a possible therapeutic option for sarcopenia
The central role of muscle stem cells in regenerative failure with aging
Frontiers Contribution of muscle satellite cells to sarcopenia
Adult stem cell sources for skeletal and smooth muscle tissue engineering, Stem Cell Research & Therapy
Focus on frailty: New senolytic holds potential for sarcopenia treatment
Trans-differentiation of muscle-derived stem cells. Possible
Muscle Cells (Myocyte) - Physiopedia
Muscle Stem Cells Derived from Benign Tumor
Adult stem cell sources for skeletal and smooth muscle tissue engineering, Stem Cell Research & Therapy
Post-Workout Muscle Recovery: How to Let Your Muscles Heal and Why
3 Tips on How to Speed Up Muscle Recovery after a Workout : r/Boostcamp
Full Abdominoplasty with Muscle Repair Surgery
- Nick Lachey weighs in on ex-wife Jessica Simpson's bestselling
- Veille Women's Underwire Saks Blue Lace Bra Set - Trendyol
- DOBREVA Women's Push Up Bra Lace Full Coverage Plunge Padded Support Underwire Bras Add 1.5 Cup Beige 32B at Women's Clothing store
- Maternity Photo Gallery - JCPenney Portraits Pregnancy photoshoot, Maternity portraits, Maternity photography tips
- New Isaac Mizrahi IM13002 Demi T-Shirt Bra 36C Lace Animal Print
- Air Control Padded Cup Sports Bra White 30AA